Ţichindeleanu studied philosophy in Cluj-Napoca (Babes-Bolyai University), Strasbourg (Marc Bloch University) and Binghamton (State University of New York) where he gained PhD in philosophy with the thesis The Graphic Sound: An Archeology of Sound, Technology and Knowledge at 1900 (2009) .
He co-founded the independent journal Philosophy & Stuff (1997-2001), the Romanian Indymedia platform in 2004, the Romanian left-wing site CriticAtac (2010), and the Eastern European left-wing political platform, LeftEast (2013). Ţichindeleanu is one of the driving forces behind the Idea Publishing House in Cluj Napoca and the Centre for the Study of Modernity and the Rural World in Telciu, the latter being the organiser of the Telciu Summer Conferences and the Telciu Summer School. He is a co-editor of The Anticommunist Illusion (Chişinău: Cartier, 2008), Romanian Revolution Televised: Contributions to the Cultural History of Media (with Konrad Petrovszky, IDEA, 2009/2011) and the author of Contracultură: rudimente de filosofie critică [Counterculture. Thoughts on Critical Philosophy] (IDEA, 2016). He translated into Romanian books by Silvia Federici, Sylvia Marcos, Walter Mignolo, Arturo Escobar, Lewis Gordon, Immanuel Wallerstein, Ivan Illich, Gilles Deleuze, and Peter Sloterdijk.
He was a member of the Governing Board of the El Taller International NGO. He participated in the 51st Venice Biennale (2005), Documenta 12 (2007), U-Turn (Copenhagen 2008). (2020)