She has (the equivalent of) a B.A. in architecture from Sint-Lucas (now known as WENK, Hogeschool Kunst en Wetenschappen), Ghent, Belgium (1994), and received an M.A. in art history (Kunstwetenschappen) from Ghent University with her dissertation ‘Web-specific art: the World Wide Web as an artistic medium’ (1997). She has also researched the design of participatory web-based resources at the Jan van Eyck Academie in Maastricht.
Sandra worked briefly at Madoc bvba (Ghent) as content and interface designer (1997). Later she was employed as web designer, webmistress, educator and educational technologist at the Teacher Training Department, Ghent University (1997-2000). Together with Guy van Belle she ran dBONANZAh!, a Flemish non-proﬁt media art initiative focusing on digital audio projects and other related subjects (1998-2002). From 2000 to 2007 she was a media archivist at V2_, Rotterdam, where she designed a description model for electronic art activities, developed a thesaurus on media art, and worked on various research projects related to subjects such as alternative copyright models and the preservation of electronic art. Later she worked at the collection and mediatheque department of NIMk, Amsterdam (2007-2012). Currently she is the project lead of the successful online video channel ArtTube, launched by Museum Boijmans van Beuningen, Rotterdam, as well as a board member of Wikimedia Netherlands, focusing on projects that involve Wikipedia/Wikimedia and cultural and heritage institutions (GLAM).
She has published and lectured extensively on the subject of internet art and media art.